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Hypomaturation Enamel Defects in Klk4 Knockout/LacZ Knockin Mice

Kallikrein 4 (Klk4) is believed to play an essential role in enamel biomineralization, because defects in KLK4 cause hypomaturation amelogenesis imperfecta. We used gene targeting to generate a knockin mouse that replaces the Klk4 gene sequence, starting at the translation initiation site, with a la...

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Detalhes bibliográficos
Main Authors: Simmer, James P., Hu, Yuanyuan, Lertlam, Rangsiyakorn, Yamakoshi, Yasuo, Hu, Jan C.-C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707199/
https://ncbi.nlm.nih.gov/pubmed/19578120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013623
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