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Reconstitution of Rad53 Activation by Mec1 through Adaptor Protein Mrc1
Upon DNA replication stress, stalled DNA replication forks serve as a platform to recruit many signaling proteins, leading to the activation of the DNA replication checkpoint. Activation of Rad53, a key effector kinase in the budding yeast Saccharomyces cerevisiae, is essential for stabilizing DNA r...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707194/ https://ncbi.nlm.nih.gov/pubmed/19457865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018242 |
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