Elevated glycogen synthase kinase-3 activity in Fragile X mice: Key metabolic regulator with evidence for treatment potential

Significant advances have been made in understanding the underlying defects of and developing potential treatments for Fragile X syndrome (FXS), the most common heritable mental retardation. It has been shown that neuronal metabotropic glutamate receptor 5 (mGluR5)-mediated signaling is affected in...

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Bibliografiske detaljer
Main Authors: Min, Wenzhong William, Yuskaitis, Christopher J., Yan, Qijiang, Sikorski, Christopher, Chen, Shengqiang, Jope, Richard S., Bauchwitz, Robert P.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707186/
https://ncbi.nlm.nih.gov/pubmed/18952114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.09.017
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