Genotypes in matrix metalloproteinase 9 are a risk factor for COPD

A growing body of evidence indicates that matrix metalloproteinases (MMPs) play a role in the pathogenesis of COPD. Therefore, we conducted a candidate gene association study of 4 promoter polymorphisms that are known to modify expression levels of the MMP-1, MMP-2, and MMP-9 genes and a Gln279Arg p...

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Bibliographische Detailangaben
Hauptverfasser: Tesfaigzi, Yohannes, Myers, Orrin B, Stidley, Christine A, Schwalm, Kurt, Picchi, Maria, Crowell, Richard E, Gilliland, Frank D, Belinsky, Steven A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2006
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707156/
https://ncbi.nlm.nih.gov/pubmed/18046864
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