Colorectal Cancer Is a Paracrine Deficiency Syndrome Amenable to Oral Hormone Replacement Therapy

The most commonly lost gene products in colorectal carcinogenesis include the paracrine hormones guanylin and uroguanylin, the endogenous ligands for guanylyl cyclase C (GCC), the intestinal receptor for diarrheagenic bacterial enterotoxins. Recently, GCC‐cyclic guanosine monophosphate (GMP) signali...

Full description

Saved in:
Bibliographic Details
Main Authors: Li, Peng, Lin, Jieru E., Snook, Adam E., Gibbons, Ahmara V., Zuzga, David S., Schulz, Stephanie, Pitari, Giovanni M., Waldman, Scott A.
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Inc 2008
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707021/
https://ncbi.nlm.nih.gov/pubmed/19727435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2008.00040.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items