NRP/Optineurin Cooperates with TAX1BP1 to Potentiate the Activation of NF-κB by Human T-Lymphotropic Virus Type 1 Tax Protein

Nuclear factor (NF)-κB is a major survival pathway engaged by the Human T-Lymphotropic Virus type 1 (HTLV-1) Tax protein. Tax1 activation of NF-κB occurs predominantly in the cytoplasm, where Tax1 binds NF-κB Essential Modulator (NEMO/IKKγ) and triggers the activation of IκB kinases. Several indepen...

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Hoofdauteurs: Journo, Chloé, Filipe, Josina, About, Frédégonde, Chevalier, Sébastien A., Afonso, Philippe V., Brady, John N., Flynn, David, Tangy, Frédéric, Israël, Alain, Vidalain, Pierre-Olivier, Mahieux, Renaud, Weil, Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2009
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706988/
https://ncbi.nlm.nih.gov/pubmed/19609363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000521
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