A Transgenic Drosophila melanogaster Model To Study Human T-Lymphotropic Virus Oncoprotein Tax-1-Driven Transformation In Vivo

Human T-cell lymphotropic virus type 1 (HTLV-1)-induced adult T-cell leukemia/lymphoma is an aggressive malignancy. HTLV-2 is genetically related to HTLV-1 but does not cause any malignant disease. HTLV-1 Tax transactivator (Tax-1) contributes to leukemogenesis via NF-κB. We describe transgenic Dros...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Shirinian, Margret, Kambris, Zakaria, Hamadeh, Lama, Grabbe, Caroline, Journo, Chloé, Mahieux, Renaud, Bazarbachi, Ali
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Transformation and Oncogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505646/
https://ncbi.nlm.nih.gov/pubmed/25995252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00918-15
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