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Trans-presentation of IL-15 by intestinal epithelial cells drives development of CD8αα IELs
IL-15 is crucial for the development of intestinal intraepithelial lymphocytes (IEL) and delivery is mediated by a unique mechanism known as trans-presentation. Parenchymal cells have a major role in the trans-presentation of IL-15 to IELs, but the specific identity of this cell type is unknown. To...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706935/ https://ncbi.nlm.nih.gov/pubmed/19553528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900420 |
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