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Potentiating Effect of Eszopiclone on GABA(A) Receptor-Mediated Responses in Pedunculopontine Neurons

The pedunculopontine nucleus (PPN) is part of the cholinergic arm of the reticular activating system, which is mostly active during waking and REM sleep. GABAergic modulation of this area appears to regulate sleep-wake cycles. Eszopiclone (ESZ), a nonbenzodiazepine hypnotic agent, appears to modulat...

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Bibliografiske detaljer
Main Authors: Ye, Meijun, Garcia-Rill, Edgar
Format: Artigo
Sprog:Inglês
Udgivet: Associated Professional Sleep Societies, LLC 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706897/
https://ncbi.nlm.nih.gov/pubmed/19639750
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