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Potentiating Effect of Eszopiclone on GABA(A) Receptor-Mediated Responses in Pedunculopontine Neurons

The pedunculopontine nucleus (PPN) is part of the cholinergic arm of the reticular activating system, which is mostly active during waking and REM sleep. GABAergic modulation of this area appears to regulate sleep-wake cycles. Eszopiclone (ESZ), a nonbenzodiazepine hypnotic agent, appears to modulat...

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Detalhes bibliográficos
Main Authors: Ye, Meijun, Garcia-Rill, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706897/
https://ncbi.nlm.nih.gov/pubmed/19639750
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