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Copy-number variation in BMPR2 is not associated with the pathogenesis of pulmonary arterial hypertension
BACKGROUND: Copy-number variations (CNVs) are structural variations in the genome involving 1 kb to 3 mb of DNA. CNV has been reported within intron 1 of the BMPR2 gene. We propose that CNV could affect phenotype in familial and/or sporadic pulmonary arterial hypertension (PAH) by altering gene expr...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706815/ https://ncbi.nlm.nih.gov/pubmed/19531247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-58 |
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