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More Radical Amino Acid Replacements in Primates than in Rodents: Support for the Evolutionary Role of Effective Population Size
We examined the pattern of nucleotide substitution in 4933 conserved single-copy orthologous protein-coding genes of human, rhesus, mouse, and rat. Consistent with previous studies, the median ratio of the number of nonsynonymous substitutions per nonsynonymous site (d(N)) to the number of synonymou...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706701/ https://ncbi.nlm.nih.gov/pubmed/19332110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2009.03.012 |
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