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More than two decades of Apc modeling in rodents

Mutation of tumor suppressor gene Adenomatous polyposis coli (APC) is an initiating step in most colon cancers. This review summarizes Apc models in mice and rats, with particular concentration on those most recently developed, phenotypic variation among different models, and genotype/ phenotype cor...

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Bibliografische gegevens
Hoofdauteurs: Zeineldin, Maged, Neufeld, Kristi L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655098/
https://ncbi.nlm.nih.gov/pubmed/23333833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2013.01.001
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