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More than two decades of Apc modeling in rodents
Mutation of tumor suppressor gene Adenomatous polyposis coli (APC) is an initiating step in most colon cancers. This review summarizes Apc models in mice and rats, with particular concentration on those most recently developed, phenotypic variation among different models, and genotype/ phenotype cor...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3655098/ https://ncbi.nlm.nih.gov/pubmed/23333833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2013.01.001 |
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