Loading...

More than two decades of Apc modeling in rodents

Mutation of tumor suppressor gene Adenomatous polyposis coli (APC) is an initiating step in most colon cancers. This review summarizes Apc models in mice and rats, with particular concentration on those most recently developed, phenotypic variation among different models, and genotype/ phenotype cor...

Full description

Saved in:
Bibliographic Details
Main Authors: Zeineldin, Maged, Neufeld, Kristi L.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655098/
https://ncbi.nlm.nih.gov/pubmed/23333833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2013.01.001
Tags: Add Tag
No Tags, Be the first to tag this record!