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Defective pulmonary vascular remodeling in Smad8 mutant mice

Pulmonary artery hypertension (PAH), a progressive, lethal condition that results in pathologic changes in the pulmonary arterial tree, eventually leads to right heart failure. Work identifying mutations in the Type II Bone morphogenetic protein (Bmp) receptor, BmpRII, in families with PAH has impli...

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Detalhes bibliográficos
Main Authors: Huang, Zheng, Wang, Degang, Ihida-Stansbury, Kaori, Jones, Peter Lloyd, Martin, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706683/
https://ncbi.nlm.nih.gov/pubmed/19419974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp214
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