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Defective pulmonary vascular remodeling in Smad8 mutant mice
Pulmonary artery hypertension (PAH), a progressive, lethal condition that results in pathologic changes in the pulmonary arterial tree, eventually leads to right heart failure. Work identifying mutations in the Type II Bone morphogenetic protein (Bmp) receptor, BmpRII, in families with PAH has impli...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706683/ https://ncbi.nlm.nih.gov/pubmed/19419974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp214 |
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