Monitoring Copopulated Conformational States During Protein Folding Events Using Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry

The precise mechanism of protein folding remains elusive and there is a deficiency of biophysical techniques that are capable of monitoring the individual behavior of copopulated protein conformers during the folding process. Herein, an ion mobility spectrometry (IMS) device integrated with electros...

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Detalhes bibliográficos
Main Authors: Smith, David P., Giles, Kevin, Bateman, Robert H., Radford, Sheena E., Ashcroft, Alison E.
Formato: Artigo
Idioma:Inglês
Publicado em: ACS Publications 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706321/
https://ncbi.nlm.nih.gov/pubmed/17964800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2007.09.017
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