Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves

INTRODUCTION: Extracellular matrix changes occur in many heart valve pathologies. For example, myxomatous mitral valves are reported to contain excess proteoglycans (PGs) and hyaluronan (HA). However, it is unknown which specific PGs are altered in myxomatous valves. Because PGs perform varied funct...

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Hauptverfasser: Gupta, Vishal, Barzilla, Janet E., Mendez, Joe S., Stephens, Elizabeth H., Lee, Elaine L., Collard, C. David, Laucirica, Rodolfo, Weigel, Paul H., Grande-Allen, K. Jane
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706283/
https://ncbi.nlm.nih.gov/pubmed/18621549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2008.05.001
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