Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves

INTRODUCTION: Extracellular matrix changes occur in many heart valve pathologies. For example, myxomatous mitral valves are reported to contain excess proteoglycans (PGs) and hyaluronan (HA). However, it is unknown which specific PGs are altered in myxomatous valves. Because PGs perform varied funct...

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Main Authors: Gupta, Vishal, Barzilla, Janet E., Mendez, Joe S., Stephens, Elizabeth H., Lee, Elaine L., Collard, C. David, Laucirica, Rodolfo, Weigel, Paul H., Grande-Allen, K. Jane
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706283/
https://ncbi.nlm.nih.gov/pubmed/18621549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2008.05.001
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