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Upregulation of the creatine synthetic pathway in skeletal muscles of mature mdx mice

Duchenne muscular dystrophy (DMD) is a fatal neuromuscular human disease caused by dystrophin deficiency. The mdx mouse lacks dystrophin protein, yet does not exhibit the debilitating DMD phenotype. Investigating compensatory mechanisms in the mdx mouse is important. This study targets two metabolic...

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Autores principales: McClure, Warrren C., Rabon, Rick, Ogawa, Hirofumi, Tseng, Brian S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706264/
https://ncbi.nlm.nih.gov/pubmed/17588756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2007.04.008
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