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Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects

Proteases play important roles in a variety of pathologies from heart disease to cancer. Quantitative measurement of protease activity is possible using a novel spectrally matched dual fluorophore probe and a small animal lifetime imager. The recorded fluorescence from an activatable fluorophore, on...

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Detalhes bibliográficos
Main Authors: Salthouse, Christopher D., Reynolds, Fred, Tam, Jenny M., Josephson, Lee, Mahmood, Umar
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706141/
https://ncbi.nlm.nih.gov/pubmed/20161242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.snb.2009.02.037
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