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Spectrum of mitochondrial DNA deletions within the Common Deletion region induced by low levels of UVB irradiation of human keratinocytes in vitro
We show that a single low-dose exposure of human epidermal keratinocytes (NHEK) to an FS20 light source in vitro can induce the formation of mitochondrial DNA deletions in a PCR detection assay. We used primer sets specifically designed to exclude amplification of segments containing the common dele...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706008/ https://ncbi.nlm.nih.gov/pubmed/19345726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2009.03.019 |
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