An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice

Progressive hearing loss is common in the human population, but little is known about the molecular basis. We report a new ENU-induced mouse mutant, diminuendo, with a single base change in the seed region of Mirn96. Heterozygotes show progressive loss of hearing and hair cell anomalies, while homoz...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lewis, Morag A, Quint, Elizabeth, Glazier, Anne M, Fuchs, Helmut, De Angelis, Martin Hrabé, Langford, Cordelia, van Dongen, Stijn, Abreu-Goodger, Cei, Piipari, Matias, Redshaw, Nick, Dalmay, Tamas, Pelayo, Miguel Angel Moreno, Enright, Anton J, Steel, Karen P
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705913/
https://ncbi.nlm.nih.gov/pubmed/19363478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.369
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker