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Three Distinct Stages of Apoptotic Nuclear Condensation Revealed by Time-Lapse Imaging, Biochemical and Electron Microscopy Analysis of Cell-Free Apoptosis

During apoptotic execution, chromatin undergoes a phase change from a heterogeneous, genetically active network to an inert highly condensed form that is fragmented and packaged into apoptotic bodies. We have previously used a cell-free system to examine the roles of caspases or other proteases in a...

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Main Authors: Toné, Shigenobu, Sugimoto, Kenji, Tanda, Kazue, Suda, Taiji, Uehira, Kenzo, Kanouchi, Hiroaki, Samejima, Kumiko, Minatogawa, Yohsuke, Earnshaw, William C.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705844/
https://ncbi.nlm.nih.gov/pubmed/17643424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.06.018
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