Arrhythmogenic actions of the Ca(2+) channel agonist FPL-64716 in Langendorff-perfused murine hearts

The experiments explored the extent to which alterations in L-type Ca(2+) channel-mediated Ca(2+) entry triggers Ca(2+)-mediated arrhythmogenesis in Langendorff-perfused murine hearts through use of the specific L-type Ca(2+) channel modulator FPL-64716 (FPL). Introduction of FPL (1 μm) resulted in...

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Bibliographic Details
Main Authors: Ghais, Nina S, Zhang, Yanmin, Grace, Andrew A, Huang, Christopher L-H
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
Subjects:
Heart/Cardiac Muscle
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705814/
https://ncbi.nlm.nih.gov/pubmed/18978037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2008.044669
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