In Vitro Evaluation of Oxoplatin: An Oral Platinum(IV) Anticancer Agent

Platinum(IV) compounds like oxoplatin (cis, cis, trans-diammine-dichlorido-dihydroxido-platinum(IV)) show increased stability and therefore can be applied orally. In a panel of 38 human cancer cell lines this drug induced S-phase arrest and cell death with IC(50) values 2.5-fold higher than cisplati...

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Detalhes bibliográficos
Main Authors: Olszewski, Ulrike, Ach, Florian, Ulsperger, Ernst, Baumgartner, Gerhard, Zeillinger, Robert, Bednarski, Patrick, Hamilton, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705772/
https://ncbi.nlm.nih.gov/pubmed/19587824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/348916
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