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Global distribution of conformational states derived from redundant models in the PDB points to non-uniqueness of the protein structure

It is commonly accepted that proteins have evolutionarily conserved 3-dimensional structures, uniquely defined by their amino acid sequence. Here, we question the direct association of structure to sequence by comparing multiple models of identical proteins. Rapidly growing structural databases cont...

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Detalhes bibliográficos
Main Authors: Burra, Prasad V., Zhang, Ying, Godzik, Adam, Stec, Boguslaw
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705611/
https://ncbi.nlm.nih.gov/pubmed/19553204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812152106
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