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Global distribution of conformational states derived from redundant models in the PDB points to non-uniqueness of the protein structure
It is commonly accepted that proteins have evolutionarily conserved 3-dimensional structures, uniquely defined by their amino acid sequence. Here, we question the direct association of structure to sequence by comparing multiple models of identical proteins. Rapidly growing structural databases cont...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705611/ https://ncbi.nlm.nih.gov/pubmed/19553204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812152106 |
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