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Adiabatic coarse-graining and simulations of stochastic biochemical networks

We propose a universal approach for analysis and fast simulations of stiff stochastic biochemical networks, which rests on elimination of fast chemical species without a loss of information about mesoscopic, non-Poissonian fluctuations of the slow ones. Our approach is similar to the Born–Oppenheime...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sinitsyn, N. A., Hengartner, Nicolas, Nemenman, Ilya
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705573/
https://ncbi.nlm.nih.gov/pubmed/19525397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809340106
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