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Mixed-integer nonlinear optimisation approach to coarse-graining biochemical networks

Quantitative modelling and analysis of biochemical networks is challenging because of the inherent complexities and nonlinearities of the system and the limited availability of parameter values. Even if a mathematical model of the network can be developed, the lack of large-scale good-quality data m...

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Autori principali: Maurya, M.R., Bornheimer, S.J., Venkatasubramanian, V., Subramaniam, S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749294/
https://ncbi.nlm.nih.gov/pubmed/19154082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1049/iet-syb:20080098
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