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Stronger inhibition of gastric acid secretion by lafutidine, a novel H(2) receptor antagonist, than by the proton pump inhibitor lansoprazole

AIM: To compare the antisecretory activity and plasma drug concentrations of a single oral dose of 10 mg lafutidine, a novel H(2) receptor antagonist, with those of the proton pump inhibitor lansoprazole (LPZ) 30 mg. METHODS: Ten volunteers without H pylori infection participated in this crossover s...

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Detalhes bibliográficos
Main Authors: Yamagishi, Hatsushi, Koike, Tomoyuki, Ohara, Shuichi, Horii, Toru, Kikuchi, Ryousuke, Kobayashi, Shigeyuki, Abe, Yasuhiko, Iijima, Katsunori, Imatani, Akira, Suzuki, Kaori, Hishinuma, Takanori, Goto, Junichi, Shimosegawa, Tooru
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705098/
https://ncbi.nlm.nih.gov/pubmed/18416470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.2406
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