Early effects of Lansoprazole orally disintegrating tablets on intragastric pH in CYP2C19 extensive metabolizers

AIM: To compare rabeprazole (RPZ; 10 mg) with Lansoprazole orally disintegrating tablets (LPZ; 30 mg OD) in terms of antisecretory activity and blood drug concentration after a single dose. METHODS: Eight H pylori-negative cytochrome P450 (CYP) 2C19 extensive metabolizers were assigned to receive a...

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Hauptverfasser: Yamagishi, Hatsushi, Koike, Tomoyuki, Ohara, Shuichi, Horii, Toru, Kikuchi, Ryousuke, Kobayashi, Shigeyuki, Abe, Yasuhiko, Iijima, Katsunori, Imatani, Akira, Suzuki, Kaori, Hishinuma, Takanori, Goto, Junichi, Shimosegawa, Tooru
Format: Artigo
Sprache:Inglês
Veröffentlicht: The WJG Press and Baishideng 2008
Schlagworte:
Rapid Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701526/
https://ncbi.nlm.nih.gov/pubmed/18395905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.2049
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