Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro

AIM: To investigate the effect and mechanism of blockade of the CXC chemokine receptor-4 (CXCR4) signaling pathway by AMD3100, a small non-peptide CXCR4 inhibitor, on invasion and metastasis of colorectal cancer cells in vitro. METHODS: Human colorectal cancer cell line SW480 was treated with AMD310...

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Main Authors: Li, Ji-Kun, Yu, Liang, Shen, Yun, Zhou, Li-Sheng, Wang, Yi-Cheng, Zhang, Jian-Hai
Format: Artigo
Sprog:Inglês
Udgivet: The WJG Press and Baishideng 2008
Fag:
Colorectal Cancer
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705083/
https://ncbi.nlm.nih.gov/pubmed/18416455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.2308
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