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The CXCR4 Antagonist AMD3100 Has Dual Effects on Survival and Proliferation of Myeloma Cells In Vitro

PURPOSE: AMD3100, an antagonist of the CXCR4 chemokine receptor is soon to be used clinically for the peripheral mobilization of hematopoietic stem cells (HSCs) in patients with multiple myeloma. AMD3100 has been shown to activate a G protein coupled with CXCR4 and thus acts as a partial CXCR4 agoni...

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Bibliografiske detaljer
Main Authors: Kim, Ha-Yon, Hwang, Ji-Young, Kim, Seong-Woo, Lee, Hyo-Jin, Yun, Hwan-Jung, Kim, Samyong, Jo, Deog-Yeon
Format: Artigo
Sprog:Inglês
Udgivet: Korean Cancer Association 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021742/
https://ncbi.nlm.nih.gov/pubmed/21253325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2010.42.4.225
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