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High-Level Biosynthesis of the Anteiso-C(17) Isoform of the Antibiotic Mycosubtilin in Bacillus subtilis and Characterization of Its Candidacidal Activity

High-level production (880 mg liter(−1)) and isolation of the anteiso-C(17) isoform of the lipopeptide mycosubtilin produced by a genetically engineered Bacillus subtilis strain are reported. Antifungal activity of this isoform, as determined via culture and fluorometric and cell leakage assays, sug...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Fickers, Patrick, Guez, Jean-Sébastien, Damblon, Christian, Leclère, Valérie, Béchet, Max, Jacques, Philippe, Joris, Bernard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704807/
https://ncbi.nlm.nih.gov/pubmed/19429561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00548-09
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