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Antibodies to the Buried N Terminus of Rhinovirus VP4 Exhibit Cross-Serotypic Neutralization

Development of a vaccine for the common cold has been thwarted by the fact that there are more than 100 serotypes of human rhinovirus (HRV). We previously demonstrated that the HRV14 capsid is dynamic and transiently displays the buried N termini of viral protein 1 (VP1) and VP4. Here, further evide...

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Detalhes bibliográficos
Main Authors: Katpally, Umesh, Fu, Tong-Ming, Freed, Daniel C., Casimiro, Danilo R., Smith, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704786/
https://ncbi.nlm.nih.gov/pubmed/19403680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00557-09
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