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Antibodies to the Buried N Terminus of Rhinovirus VP4 Exhibit Cross-Serotypic Neutralization

Development of a vaccine for the common cold has been thwarted by the fact that there are more than 100 serotypes of human rhinovirus (HRV). We previously demonstrated that the HRV14 capsid is dynamic and transiently displays the buried N termini of viral protein 1 (VP1) and VP4. Here, further evide...

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Autores principales: Katpally, Umesh, Fu, Tong-Ming, Freed, Daniel C., Casimiro, Danilo R., Smith, Thomas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704786/
https://ncbi.nlm.nih.gov/pubmed/19403680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00557-09
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