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Nef-Induced CD4 Endocytosis in Human Immunodeficiency Virus Type 1 Host Cells: Role of p56(lck) Kinase

Human immunodeficiency virus type 1 (HIV-1) Nef interferes with the endocytic machinery to modulate the cell surface expression of CD4. However, the basal trafficking of CD4 is governed by different rules in the target cells of HIV-1: whereas CD4 is rapidly internalized from the cell surface in myel...

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Detalhes bibliográficos
Main Authors: Laguette, Nadine, Brégnard, Christelle, Bouchet, Jérôme, Benmerah, Alexandre, Benichou, Serge, Basmaciogullari, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704780/
https://ncbi.nlm.nih.gov/pubmed/19439470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01648-08
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