Divergent Bro1 Domains Share the Capacity To Bind Human Immunodeficiency Virus Type 1 Nucleocapsid and To Enhance Virus-Like Particle Production

To promote the release of infectious virions, human immunodeficiency virus type 1 (HIV-1) exploits the endosomal sorting complex required for transport (ESCRT) pathway by engaging Tsg101 and ALIX through late assembly (L) domains in p6 Gag. An LYPx(n)L motif in p6 serves as docking site for the cent...

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Bibliographic Details
Main Authors: Popov, Sergei, Popova, Elena, Inoue, Michio, Göttlinger, Heinrich G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704772/
https://ncbi.nlm.nih.gov/pubmed/19403673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00198-09
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