Delivery of Human Immunodeficiency Virus Vaccine Vectors to the Intestine Induces Enhanced Mucosal Cellular Immunity

Effective vaccines for human immunodeficiency virus type 1 (HIV-1) will likely need to stimulate protective immunity in the intestinal mucosa, where HIV-1 infection causes severe CD4(+) T-cell depletion. While replication-competent recombinant adenovirus (rAd) vectors can stimulate adenovirus-specif...

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Detalhes bibliográficos
Main Authors: Wang, Lingshu, Cheng, Cheng, Ko, Sung-Youl, Kong, Wing-Pui, Kanekiyo, Masaru, Einfeld, David, Schwartz, Richard M., King, C. Richter, Gall, Jason G. D., Nabel, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704769/
https://ncbi.nlm.nih.gov/pubmed/19420074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00374-09
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