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Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of Rheb

The mammalian target of rapamycin (mTOR) interacts with raptor to form the protein complex mTORC1 (mTOR complex 1), which plays a central role in the regulation of cell growth in response to environmental cues. Given that glucose is a primary fuel source and a biosynthetic precursor, how mTORC1 sign...

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Autores principales: Lee, Mi Nam, Ha, Sang Hoon, Kim, Jaeyoon, Koh, Ara, Lee, Chang Sup, Kim, Jung Hwan, Jeon, Hyeona, Kim, Do-Hyung, Suh, Pann-Ghill, Ryu, Sung Ho
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704738/
https://ncbi.nlm.nih.gov/pubmed/19451232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00165-09
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