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Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of Rheb
The mammalian target of rapamycin (mTOR) interacts with raptor to form the protein complex mTORC1 (mTOR complex 1), which plays a central role in the regulation of cell growth in response to environmental cues. Given that glucose is a primary fuel source and a biosynthetic precursor, how mTORC1 sign...
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Autores principales: | , , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
American Society for Microbiology (ASM)
2009
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704738/ https://ncbi.nlm.nih.gov/pubmed/19451232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00165-09 |
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