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Essential Role for Schizosaccharomyces pombe pik1 in Septation

BACKGROUND: Schizosaccharomyces pombe pik1 encodes a phosphatidylinositol 4-kinase, reported to bind Cdc4, but not Cdc4(G107S). PRINCIPAL FINDINGS: Gene deletion revealed that pik1 is essential. In cells with pik1 deleted, ectopic expression of a loss-of-function allele, created by fusion to a tempe...

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Detalhes bibliográficos
Main Authors: Park, Jae-Sook, Steinbach, Sarah K., Desautels, Michel, Hemmingsen, Sean M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704394/
https://ncbi.nlm.nih.gov/pubmed/19587793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006179
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