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Biophysical Mechanism for Ras-Nanocluster Formation and Signaling in Plasma Membrane

Ras GTPases are lipid-anchored G proteins, which play a fundamental role in cell signaling processes. Electron micrographs of immunogold-labeled Ras have shown that membrane-bound Ras molecules segregate into nanocluster domains. Several models have been developed in attempts to obtain quantitative...

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Detalhes bibliográficos
Main Authors: Gurry, Thomas, Kahramanoğulları, Ozan, Endres, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704371/
https://ncbi.nlm.nih.gov/pubmed/19587789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006148
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