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Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers

Aberrant promoter hypermethylation is one of the major mechanisms in carcinogenesis and some critical growth regulatory genes have shown commonality in methylation across solid tumors. Twenty-six genes, 14 identified through methylation in colon and breast cancers, were evaluated using primary lung...

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Hlavní autoři: Tessema, Mathewos, Yu, Yang Y., Stidley, Christine A., Machida, Emi O., Schuebel, Kornel E., Baylin, Stephen B., Belinsky, Steven A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704285/
https://ncbi.nlm.nih.gov/pubmed/19435948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp114
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