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Vitamin C and α-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats

The mechanisms underlying the pathogenesis of estrogen-induced breast carcinogenesis remain unclear. The present study investigated the roles of estrogen metabolism and oxidative stress in estrogen-mediated mammary carcinogenesis in vivo. Female August Copenhagen Irish (ACI) rats were treated with 1...

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Detalhes bibliográficos
Main Authors: Mense, Sarah M., Singh, Bhupendra, Remotti, Fabrizio, Liu, Xinhua, Bhat, Hari K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704283/
https://ncbi.nlm.nih.gov/pubmed/19406931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp093
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