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Partial Inhibition of Estrogen-Induced Mammary Carcinogenesis in Rats by Tamoxifen: Balance between Oxidant Stress and Estrogen Responsiveness

Epidemiological and experimental evidences strongly support the role of estrogens in breast tumor development. Both estrogen receptor (ER)-dependent and ER-independent mechanisms are implicated in estrogen-induced breast carcinogenesis. Tamoxifen, a selective estrogen receptor modulator is widely us...

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Hlavní autoři: Singh, Bhupendra, Bhat, Nimee K., Bhat, Hari K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180376/
https://ncbi.nlm.nih.gov/pubmed/21966433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025125
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