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Alterations of histone modifications by cobalt compounds

In the present study, we examined the effects of CoCl(2) on multiple histone modifications at the global level. We found that in both human lung carcinoma A549 cells and human bronchial epithelial Beas-2B cells, exposure to CoCl(2) (≥200 μM) for 24 h increased H3K4me3, H3K9me2, H3K9me3, H3K27me3, H3...

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Bibliographic Details
Main Authors: Li, Qin, Ke, Qingdong, Costa, Max
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704281/
https://ncbi.nlm.nih.gov/pubmed/19376846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp088
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