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Prostaglandin F2α promotes muscle cell survival and growth through upregulation of the inhibitor of apoptosis protein BRUCE

During skeletal muscle growth and regeneration, the majority of differentiating myoblasts undergoes cell-cell fusion to form multinucleated myofibers, while a proportion of myoblasts undergoes apoptosis. The treatment of myoblasts with prostaglandin F2α (PGF2α) during myogenesis in vitro leads to th...

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Bibliographic Details
Main Authors: Jansen, Katie M., Pavlath, Grace K.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704066/
https://ncbi.nlm.nih.gov/pubmed/18566603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2008.90
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