Prostaglandin F(2α) elevates blood pressure and promotes atherosclerosis

Little is known about prostaglandin F(2α) in cardiovascular homeostasis. Prostaglandin F(2α) dose-dependently elevates blood pressure in WT mice via activation of the F prostanoid (FP) receptor. The FP is expressed in preglomerular arterioles, renal collecting ducts, and the hypothalamus. Deletion o...

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Autores principales: Yu, Ying, Lucitt, Margaret B., Stubbe, Jane, Cheng, Yan, Friis, Ulla G., Hansen, Pernille B., Jensen, Boye L., Smyth, Emer M., FitzGerald, Garret A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673134/
https://ncbi.nlm.nih.gov/pubmed/19416858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811834106
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