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HPMA Copolymer–Doxorubicin–Gadolinium Conjugates: Synthesis, Characterization, and in vitro Evaluation

This study describes the synthesis, characterization, and in vitro evaluation of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer–gadolinium (Gd)–doxorubicin (Dox) conjugates. Copolymers of HPMA were derivatized to incorporate side chains for Gd chelation and Dox conjugation. The conjugates were c...

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Detalhes bibliográficos
Main Authors: Zarabi, Bahar, Nan, Anjan, Zhuo, Jiachen, Gullapalli, Rao, Ghandehari, Hamidreza
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704051/
https://ncbi.nlm.nih.gov/pubmed/18484565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.200700290
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