Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain

Signal transducer and activator of transcription (Stat) proteins are latent transcription factors that reside in the cytoplasm before activation. On cytokine-induced tyrosine phosphorylation, these molecules dimerize and accumulate transiently in the nucleus. No specific signals mediating these proc...

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Bibliographische Detailangaben
Hauptverfasser: Begitt, Andreas, Meyer, Thomas, van Rossum, Marleen, Vinkemeier, Uwe
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC27039/
https://ncbi.nlm.nih.gov/pubmed/10973496
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