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Induction of Thyroid Gene Expression and Radioiodine Uptake in Melanoma Cells: Novel Therapeutic Implications

Both the MAP kinase and PI3K/Akt pathways play an important role in the pathogenesis of melanoma. We conducted the present study to test the hypothesis that targeting the two pathways to potently induce cell inhibition accompanied with thyroid iodide-handling gene expression for adjunct radioiodine...

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Detalhes bibliográficos
Main Authors: Hou, Peng, Liu, Dingxie, Ji, Meiju, Liu, Zhi, Engles, James M., Wahl, Richard L., Xing, Mingzhao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703805/
https://ncbi.nlm.nih.gov/pubmed/19593429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006200
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